CD47/SIRPα Matched PairDRAFT

0 · PDP v3.0

Designed For: 待按 Target Pair 需求定义（PRD v3.0 §21）

Used In: 待按 Target Pair 需求定义（PRD v3.0 §21）

Workflow Step: 待按 Target Pair 需求定义（PRD v3.0 §21）

Validated With: 待按 Target Pair 需求定义（PRD v3.0 §21）

Recommended With: 待按 Target Pair 需求定义（PRD v3.0 §21）

Evidence: SEC / SPR-BLI / FACS / functional data on COA (pending M4)

1 · What is it?

Monomeric CD47 ECD + SIRPα V1 ECD (allotype stated).

2 · What is it for?

Macrophage checkpoint: blocking assays, phagocytosis, SPR/BLI.

3 · Why trust it?

µM-range KD (reported), SEC monomer state, V1/V2 allotype on COA.

4 · How to use it?

• Protocol: CD47–SIRPα SPR Binding & Antibody Blocking

5 · Related Solution

• CD47 / SIRPα Blocking Assay Design: Avoiding the Pitfalls That Invalidate Your Data

Part of Bundle · 所属套装

• CD47/SIRPα Functional Pair Ready

Product data (price / availability) pending M4 supplier confirmation.