Research Tools
Intelligence → Decision → Tool → ServiceAssay-ready proteins and tool sets selected per Target Pair demand (PRD §9: format must answer a BsAb decision or experiment).
FcRn Protein
pH-dependent binding & half-life evaluation (SPR/BLI, pH 6.0 / 7.4 dual measurement).
CD16a (V158 & F158)
FcγR binding, ADCC evaluation, variant comparison (ΔKD ratio).
IL-15 (Animal-Free)
NK/T-cell expansion, cytokine combinations (with IL-21 / IL-7).
B7-H3 (4Ig)
Checkpoint antibody discovery, ADC/BsAb target validation.
TIGIT/CD155 Matched Pair
Checkpoint antibody screening, target engagement, competition assays.
CD47/SIRPα Matched Pair
Macrophage checkpoint: blocking assays, phagocytosis, SPR/BLI.
Cytokine Bundle (IL-15/IL-21/IL-7)
NK expansion (IL-15+IL-21), T-cell memory (IL-15+IL-7), GMP roadmap.
GP Tool Sets · GP 工具套装（规格）
PRD §10: 2–6 products + 1 protocol + optional service credit — defined per Golden Pair, supply qualification pendingPD-1 × VEGF-A
PD-1 (PDCD1) ECD — mature formats
PD-L1 × VEGF-A
PD-L1 (CD274) ECD — mature formats (His/Avi/biotin)
DLL3 × CD3
DLL3 ECD — expression-difficult (tool gap: quantified yield/stability)
EGFR × LGR5
EGFR ECD (mature formats: His/Avi/biotin)
EGFR × MET
EGFR ECD — mature (Sino/ACRO human+Cyno, His/Avi/biotin)
Target Pair Tool Sets · 工具套装
Legacy tool sets · 2–6 products + 1 protocol + optional service creditHalf-Life Starter Panel
Evaluate Fc half-life extension (YTE / LS / N434A) against a WT reference in one matched set — pH 6.0/7.4 dual-buffer SPR/BLI.
Human/Cyno PK Translation Panel
Bridge human FcRn data to Cynomolgus for PK translation planning. D6: Cyno availability under supplier verification (P2 target).
TIGIT/CD155 Discovery Pair
Checkpoint antibody screening with a pre-validated matched TIGIT/CD155 pair — biotin option, DNAM-1 cross-control.
CD47/SIRPα Functional Pair
Macrophage checkpoint: CD47/SIRPα blocking, phagocytosis and SPR/BLI — allotype-stated controls, RBC-interference assay support.
T/NK Expansion Cytokine Set
Reproducible T/NK workflows: IL-15 + IL-21 (NK), IL-15 + IL-7 (T memory) — Animal-Free, ED50 per cytokine, GMP roadmap.
CD19 CAR QC Set
CAR detection and target engagement QC: CD19 + BCMA antigens plus universal detector — Avi/biotin formats under RFQ.
HSPC Core 3
HSPC expansion core: SCF + TPO + FLT3L as a matched set for CD34+ culture — quote and ED50 under RFQ.
TCE Dual-Arm Panel
Dual-arm T-cell engager characterization: CD3ε + tumor antigen + FcγR panel — scoped for P1, not yet available.